Peptides vs. retinol: which one do you need? It isn't really either/or. Peptides Retinol How it works Supports and signals the skin Speeds up cell renewal Gentleness Very gentle Can irritate at first Best for Sensitive skin, beginners, daily use Experienced users, stronger results Sun sensitivity No Yes, so SPF is essential Many people start with peptides because they're easy to tolerate. If you later want to add retinol, the two can work well together: peptides in the mornin